Papain is extracted from the raw fruit of the papaya plant. Not just for eating, this delicious fruit contains proteolytic enzymes that act as gentle exfoliators when applied to your face. Since papain’s main function is to breakdown lipids, products that contain this enzyme are ideal for congested and hyper-pigmented skin. Papain is not nearly as harsh as BHAs or AHAs, so it’s another safe choice for sensitive complexions.