The Andiroba tree is a large towering tree found in the tropical rainforests of Brazil, forming an essential part of the rainforest canopy.

Andiroba Oil has incredible moisturizing and rejuvenating properties, soothing and healing dull skin. This revitalizing oil is rich in myristic acid, which is known to promote cellular renewal. It is light and penetrates the skin quickly. It is a natural oil base for many anti-wrinkle creams by several exclusive brand names.

Renowned for its anti-inflammatory properties, it can be used to promote the circulation of blood in the skin and helps to relieve pain and swelling during an injury. It has antiviral, anti-fungal, and antibacterial properties. The Indians in the Amazon have used andiroba oil for centuries as a natural insect repellent, insect bites and stings; psoriasis, dermatitis, heat rash, skin fungi & parasites and skin cancer.

Applying the oil heated to joints can treat and relieve arthritis and rheumatism. Andiroba oil is an anti-inflammatory oil rich in skin nourishment – omega-3 fatty acids. It promotes normal circulation to the skin and relieves pain and swelling.

To get the best results from the hair oil, you need to apply it correctly. Heat some oil and apply the oil to your scalp and hair. Dip a towel in hot water and wrap it around your hair. The heat from the towel will make the hair follicles absorb the oil. Leave for up to half an hour. Then wash your hair with a mild shampoo followed by a conditioner. This treatment works wonders for dry coarse hair and helps to soften the strands and make it silky.

The seed oil of C. guianensis has traditionally been used as a household liniment for the treatment of sprains, rashes, soreness, and inflammation, as well as an insect repellent by indigenous people. In the cosmetic industry, the seed oil is used as soap, cream, massage oil, etc.

The bitter taste, the origin of the name “andiroba” in the Tupi-Guarani language, is due to limonoids, highly oxygenated and modi ed terpenoids. Limonoids (30–41) are known to have a variety of biological activities like insecticidal, antifeedant, antibacterial, antimalarial, and antiviral. Recently, a number of limonoids have been isolated from seed oil. Among them, carapanolide A (41) exhibited moderate cancer cell growth inhibition using murine L1210 leukaemia cells with IC50 8.7 μM.21

The high-performance liquid chromatography (HPLC) method, optimized by central composite design, determined the amount of four limonoids, gedunin (31), 6α-acetoxygedunin (32), 7-desacetoxy-7-ox- ogedunin (33), and methyl angolensate (37), being 33 most abundant.

The sticky and white fruit of P. insignis is consumed raw by local people and is often made into various condiments and beverages due to its distinctive taste with a pleasant odour and subacid avor. The seeds contain a high amount of oil, being used for the treatment of eczemas and herpes. In cosmetics, the oil is used as soap, skin care products, and moisturizers, but the cultivation is very limited and most of the fruit production is extractive.

Analysis of the volatile fractions of the fruits demonstrated that terpene alcohols (42–51) are the most abundant, and among them, linalool (42) and related compounds (43–51) may indicate the bio-synthetic origin.

The antioxidant and toxicity activities of the dichloromethane and ethyl acetate fractions of the ethanolic extract of the seeds were evaluated. Both fractions demonstrated in vitro anti-2,2 -azino-bis(3-ethylbenzothiazoline-6-sulphonic acid) diammonium salt (ABTS) assays, as well as in vivo effects in antioxidant- -defective Saccharomyces cerevisiae strains. These activities could be attributed to xanthones (52, 53), present in these fractions as major compounds. The xanthones isolated from other species have been reported to demonstrate anti-cancer and anti-inflammatory activities.

Garcinielliptone FC (54), a polyisoprenylated benzophenones, present in the seed of P. insignis, promoted an endothelium-independent vasorelaxation on phenylephrine-induced vasoconstriction.

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